EcoGene

GenePage for the lptA gene of Escherichia coli K-12

Primary Gene Name: lptA
EcoGene Accession Number: EG12618
K-12 Gene Accession Number: ECK3189
MG1655 Gene Identifier: b3200

Gene Name Mnemonic: LPS transport

Alternate Gene Symbols: yhbN

Description:
Periplasmic LPS-binding protein, binds Lipid A domain; LPS transport and assembly

Pre-Run BlastP UniProt

Protein Sequence: ------------ MW: 20126.88------185 aa ------------ Pre-Run BlastP NR+Env

Genomic Address
Left End: 3341402 ----------------- Clockwise ----------------- Right End: 3341959
Left Inter Gene Info Minute or Centisome (%) = 72.02 Right Inter Gene Info

PDF EcoMap

Curator or user-submitted Comments:

LptA depletion results in rifampicin/bile salts sensitivity, indicative of an outer membrane integrity defect. Paralogous to Imp. The first 27 aa are a type I signal peptide. RpoE regulon.