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EcogeneTopic Page
TopicPage for G:T mismatch binding of Escherichia coli K-12
 | Proteome Chips: Mismatch Binding |
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Description:
Chen (2008) identified the top 20 proteins that preferentially bind to dsDNA containing a G:T mismatch, called probe 3. Probe 1 is the same 19-mer without the mismatch on the upper strand.
Details:
5'-GGAATTAAAGTGAAGACC-3'
3'- CCTTAATTTCGCTTCTGG-5
The ratio of the preferential probe 3 binding ranges from 12.2 fold for CspE to 1.7 fold for YfeP. YbcN is ranked second at 7.0 fold.
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