EcogeneTopic Page
TopicPage for
Reduced Genome
of
Escherichia coli
K-12
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Minimal Genome
Description:
Strains with reduced genomes of
E. coli
K-12, such as MDS42, can have improved growth characteristics and improved yields of biotechnology products.
Details:
PEC Large Deletion Website
Reduced Genome
Bibliography (2 total) :
Review Only
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2007
Sharma SS, Campbell JW, Frisch D, Blattner FR, Harcum SW (2007) Expression of two recombinant chloramphenicol acetyltransferase variants in highly reduced genome Escherichia coli strains. Biotechnol Bioeng 98:1056-70
Chakiath CS, Esposito D (2007) Improved recombinational stability of lentiviral expression vectors using reduced-genome Escherichia coli. Biotechniques 43:466, 468, 470
